Antipyretic Action of Quinia and Alcohol

Antipyretic and antinociceptive effects of Nauclea latifolia root decoction and possible mechanisms of action.

CONTEXT  Nauclea latifolia Smith (Rubiaceae) is a small tree found in tropical areas in Africa. It is used in traditional medicine to treat malaria, epilepsy, anxiety, pain, fever, etc. OBJECTIVE  The aim of this study was to investigate the effects of Nauclea latifolia roots decoction on the peripheral and central nervous systems and its possible mechanisms of action. MATERIALS AND METHODS...

Antipyretic Action of Isatin and Its Analogues in Mice and Rats

The effects of isatin (2,3-dioxo-indole) and isatin analogues (5-methylisatin, 6-hydroxyisatin, 7-ethylisatin, N-acetylisatin) were tested on prostaglandin E2 (PGE2)-induced fever in mice and rats. Two modes of administration were tested. Isatin or an analogue was injected simultaneously with PGE2 and the development of fever was tested, or the test compound was given 30 min following PGE2 admi...

Antipyretic effect of ketoprofen.

OBJECTIVE The aim of this study was to investigate the efficacy and side effect profile of ketoprofen as well as compliance with respect to the taste of the drug and compare these parameters with those of acetaminophen and ibuprofen. METHODS A total of 301 patients between 1-14 years of age who applied to emergency rooms of three medical centers with the complaint of fever that required antip...

Alcohol and youth: time for effective action.

The problems associated with alcohol use were once largely considered to be primarily due to long-term heavy intake of ethanol. The major causes of death and hospitalization attributed to alcohol use were thought to be chronic diseases such as cirrhosis and alcohol dependence. Until recently, this view was largely supported by available research. The health benefits of alcohol consumption were ...

Community and municipal action on alcohol.